Of all the many things humans rely on plants for, surely the most curious is our use of them to change consciousness: to stimulate, calm, or completely alter the qualities of our mental experience. In this book, Michael Pollan explores three very different drugs - opium, caffeine and mescaline - and throws the fundamental strangeness of our thinking about them into sharp relief. Exploring and participating in the cultures that have grown up around these drugs, while consuming (or in the case of caffeine, trying not to consume) them, Pollan reckons with the powerful human attraction to psychoactive plants, and the equally powerful taboos.